(7-Hydroxy-benzofuran-3-yl)-acetic acid methyl ester

(7-Hydroxy-benzofuran-3-yl)-acetic acid methyl ester - Names and Identifiers

Name	methyl 2-(7-hydroxybenzofuran-3-yl)acetate
Synonyms	methyl 2-(7-hydroxybenzofuran-3-yl)acetate methyl 2-(7-hydroxy-1-benzofuran-3-yl)acetate 3-Benzofuranacetic acid, 7-hydroxy-, methyl ester (7-Hydroxy-benzofuran-3-yl)-acetic acid methyl ester
CAS	181052-63-1

(7-Hydroxy-benzofuran-3-yl)-acetic acid methyl ester - Physico-chemical Properties

Molecular Formula	C11H10O4
Molar Mass	206.19
Storage Condition	2-8℃

(7-Hydroxy-benzofuran-3-yl)-acetic acid methyl ester - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
HS Code	29321900

(7-Hydroxy-benzofuran-3-yl)-acetic acid methyl ester - Introduction

methyl 2-organic acetate, also known as HOBT-OMe, is a chemical compound. The following is its nature, use, formulation and safety information:

Nature:
-Appearance: Colorless to light yellow liquid.
-molecular formula: C11H11NO4.
-Molecular weight: 225.21g/mol.
-Melting point: 15-17 degrees Celsius.
-Boiling point: 298-300 degrees Celsius.
-Solubility: Soluble in ethanol, ether and carbon disulfide.

Use:
- HOBT-OMe is mainly used as a condensing agent in organic synthesis. It can react with aromatic aldehydes and ketones to form imines with acyl groups. This reaction system is commonly used in peptide synthesis and other organic compound synthesis processes.
-It can also be used as an additive to help increase the rate and selectivity of chemical reactions.

Method:
-The preparation of HOBT-OMe is usually obtained by reacting HOBT (2-hydroxybenzofuran-3-yl) with methanol and hydrochloric acid.

Safety Information:
- HOBT-OMe are relatively safe compounds under general conditions.
-But it is still a flammable liquid and should be avoided in contact with open flames or high temperatures.
-Use is required to comply with good laboratory practices, including wearing appropriate personal protective equipment, such as laboratory gloves and protective glasses.
-During use, avoid contact with skin, eyes and inhalation of vapors.
-In case of accidental contact with skin or eyes, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-10 22:29:15